Apart from its importance for the study of Hale's personal and professional life, the collection is one of the richest sources for the history of science in the United States in the early twentieth century. It contains a good deal of significant material relating to the theoretical and instrumental development of astrophysics and the history of the Mount Wilson and Palomar Observatories. The collection is of singular importance for the study of science and government, particularly with respect to the affairs of the National Academy of Sciences and the National Research Council. It documents much of the early history of the California Institute of Technology. Finally, it contains substantial material on the general affairs of the scientific community in the United States and Europe [from Kevles 1968].

These documents cover the years 1847 to 1953, the year of Millikan's death, but the core of the collection consists of the official papers generated by Millikan after his move to Pasadena in 1921. The collection includes more than 125,000 pages of letters, notebooks, unpublished speeches, addresses, lecture notes, and family papers.

One of the four horsemen of the evolutionary synthesis of the 1940s, Theodosius Dobzhansky played a crucial role in bridging the gap between theoretical and empirical approaches in genetics and in promoting the Neo-Darwinian synthesis. His contributions to the biological species concept and to an understanding the evolutionary dynamics of wild populations of Drosophila were fundamental to the development of modern population genetics and evolutionary thought. The Dobzhansky Papers are a remnant of the correspondence and writings of the geneticist and evolutionary biologist, Theodosius Dobzhansky. The correspondence (7.5 linear feet) provides insight into Dobzhansky's scientific, philosophical, and social views, particularly during the last decade of his life. Equally valuable are the 54 notebooks (ca.1917-1975) which comprise an almost uninterrupted self-commentary on Dobzhansky's career, replete with typescripts of personal letters and short essays sent to colleagues and friends. The collection also contains two unbound volumes of annotated "reminiscences" from the Columbia Oral History Project, 1962; two bound volumes of papers dedicated to him on his 70th birthday; and 1.5 linear feet of photographs.

One of the most influential statisticians of the twentieth century, John Wilder Tukey (1915-2000) played a key role in both the development and study of statistics. Upon receiving his Ph.D. in mathematics in 1939 from Brown University, he joined the faculty at Princeton; in 1945, he also began work at Bell Laboratories. Equally committed to both Princeton and Bell Labs, Tukey chose to work concurrently at both institutions. He was also a consultant for many companies, such as Merck and Company, Xerox Corporation, and the Educational Testing Service, and was a frequent advisor to the government for such programs as the US Census. From 1960 to 1980 he led the statistical component of NBC's election night projections. Among other projects Tukey analyzed Alfred Kinsey's research and examined data on ozone depletion. Tukey made many important contributions to the field of statistics, such as work in time series analysis, exploratory data analysis, and multiple comparisons. Through his work, Tukey developed statistical applications including the Box-and-Whisker Plot, the Stem-and-Leaf Diagram, Cooley-Tukey Fast Fourier Transforms, Tukey's Paired Comparisons and citation and permutated indices. Tukey's influence extends beyond statistics to everyday language: he was the first to use the word "software" in print and coined words such as "bit" and "linear programming." A prolific writer, John W. Tukey penned more than 500 technical papers and reports and published, among numerous other works. His collected papers amount to eight volumes of work. The Tukey Papers provides a comprehensive perspective into Tukey's professional activities from his days as a graduate student until his death in 2000. Among the material is his correspondence and his published and unpublished works. There is abundant material from Tukey's long careers at Bell Laboratories and Princeton University, including extensive lecture notes and syllabi. Also included are copious materials relating to his professional activities with such agencies as the National Research Council, the Army Records Office, Xerox PARC, Merck and Company, the President's Science Advisory Committee, and the National Academy of Sciences.

This collection of correspondence, reports, and manuscripts concerns Stalker's research in genetics and evolutionary biology, particularly the evolutionary genetics of Drosophila. Most of the letters are scientific, although the usual academic politics in various departments is mentioned. There is also material on the Society for the Study of Evolution (1970).

Between 1968 and 1978, the historian of science Horace Freeland Judson conducted extensive oral history interviews with biochemists and molecular biologists relating to the development of their field. The correspondence, transcripts of interviews, and taped interviews that comprise the Judson collection formed the research material used by Judson in his book, The Eighth Day of Creation (New York, 1979). Permission to quote must be obtained from Dr. Judson and access to some files is restricted.

The geneticist Milislav Demerec emigrated from Yugloslavia in 1919, spending nearly his entire career in the Department of Genetics at Cold Spring Harbor Laboratory. Working initially on the genetics of maize and later on Drosophila virilis, his research interests included radiation and chemical mutagenesis, and during the Second World War, penicillin and the genetics of antibiotic resistance. Demerec served as head of the laboratory at Cold Spring Harbor from 1941 until 1960. The Demerec collection contains the extant professional papers of Milislav Demerec, dating primarily from the time of his arrival at Cold Spring Harbor until his retirement. In addition to his correspondence with colleagues, the collection includes interesting material on the administration of Cold Spring Harbor laboratory during the 1940s and 1950s, data and research notes, material relating to professional organizations (e.g. Genetics Society of America, American Society of Naturalists), a lengthy series of lectures given by Demerec, and a large number of photographs pertaining to Demerec's research, but also to his colleagues and Cold Spring Harbor itself. There is also a Register of visitors to the laboratory (1927-1945) and a Milislav Demerec reprint list.

Thomas F. Anderson (1911-1991) was a biophysicist and electron microscopist whose research included Raman spectroscopy; the physiology of yeast; the biological effects of radiation; the biological applications of electron microscopy; and the genetics of bacteria, bacterial viruses, and bacteriophage. He was a Professor of Biophysics at the University of Pennsylvania and a Senior Member of the Institute for Cancer Research in Fox Chase.

The James V. Neel Papers document nearly every phase of the career of one of the founders of human population genetics in the United States. Neel was particularly thorough and organized, and retained virtually all of his significant scientific correspondence, committee reports, minutes of meetings, and drafts of manuscripts. The collection also includes data collected during Neel's work among the Xavante, Yanomanö and other indigenous populations. In a career that spanned the period from the late work of Thomas Hunt Morgan and Charles B. Davenport to the contemporary world of molecular genetics and nucleic acids, Neel knew, worked with, and corresponded with many of the most influential 20th century practitioners of genetics. The collection begins in earnest in 1943, after Neel had decided to focus on human genetics. Neel's work with Drosophila and none of his Drosophila manuscripts are found in the collection.

The Papers of Curt Stern include extensive correspondence, lectures (1920s-1970s, 1.5 boxes), autobiographical material, articles, zoological course notes, photographs, etc. Stern's various areas of scientific interest are documented in the collection: the chromosome theory of heredity, role of gene mutation and chromosome rearrangements in evolution, action and interaction of genes during individual development, and particularly his contribution to the development of human genetics as a discipline (centered on his popular and influential book, Principles of Human Genetics, 1949, 1960, 1973). Both his career in Germany and the United States is documented in his correspondence. After studying with T. H. Morgan at Columbia University on a Rockefeller Foundation Fellowship (1924-1926), Stern returned to Richard Goldschmidt's lab at the Kaiser-Wilhelm Institute (1926-1932). There is material of note in the collection concerning this period when Stern helped to establish the cytological basis of crossing over. After a short stay at the California Institute of Technology in 1932, Stern's temporary residence in the U. S. became permanent, and his later career at the University of Rochester, 1933-1947 (Chairman, Department of Zoology) and at the University of California, Berkeley, 1947-1970 (there is abundant material on the Department of Zoology) is covered in the collection. There is other material on: American Association for the Advancement of Science Inter-Society Committee on Science Foundation Legislation, 1946-1947; American Society of Human Genetics (Pres., 1957); Atomic Energy Commission (Advisory Committee for Biology and Medicine, 1950-1955); Genetics (journal); Oak Ridge National Laboratory (Advisory Committee for Biology, 1955-1968); and the Rockefeller Foundation. Stern's correspondence with friends and colleagues in Germany, England, and the U. S., during the 1920s-1930s, is of particular note as it documents not only the developments in genetics and the institutional and administrative networks supporting research, but it also offers general comments and observations on science, Germany, and politics. The photographs (2 boxes) include pictures of many prominent geneticists and scientists.